TEST METHOD FOR NON-VIABLE PARTICLE COUNTS IN ASEPTIC DISPENSING FACILITIES
Introduction:- Control of airborne contamination requires certain measures to be adopted, which are usually dictated by the type of product required at the end of…
Category: Microbiology
DIFFERENCE BETWEEN VIABLE PARTICLES AND NON-VIABLE PARTICLES
Viable Particle:- A viable particle is a particle that contains one or more living microorganisms. These can affect the sterility of the pharmaceutical product and…
ENVIRONMENT MONITORING BY SETTLE PLATES IN ASEPTIC FACILITY
Introduction:- Settle plate sampling is a direct method of assessing the likely number of microorganisms depositing onto the product or surface in a given time.…
TYPES OF MICROBIOLOGICAL SAFETY CABINETS (MSCS)
Class I:- A cabinet with a front aperture through which the operator can carry out manipulations inside the cabinet. This type of cabinet is suitable…
BIOASSAY AND ITS TYPES
Introduction:- Bioassay is defined as estimation or determination of concentration or potency of physical, chemical or biological agents by means of measuring and comparing the…
EFFECTIVENESS OF ANTIMICROBIAL PRESERVATIVES
The primary purpose of adding antimicrobial preservatives to dosage forms is to prevent adverse effects arising from contamination by micro-organisms that may be introduced inadvertently…
WHY STERILITY TEST REQUIRE 14 DAYS OF LONG INCUBATION TIME
To identify the viable contamination (bacteria, fungus, spores etc.) in the product sterility testing is the essential method. As this testing is very important, it…
RAPID METHODS FOR STERILITY TESTING
Current compendial methods for sterility testing in the pharmaceutical industry remain culture-based and include an incubation period of 14 days. Clearly, this is a delay…
TEST FOR BACTERIAL ENDOTOXINS
The bacterial endotoxins test (BET) is a test to detect or quantify endotoxins from Gram-negative bacteria using amoebocyte lysate from the horseshoe crab (Limulus polyphemus…
DIFFERENCE BETWEEN VIABLE PARTICLES AND NON-VIABLE PARTICLES 1
Viable Particle:- A viable particle is a particle that contains one or more living microorganisms. These can affect the sterility of the pharmaceutical product and…
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